Measurement of Plasma Total Homocysteine by HPLC with Coulometric Detection
نویسندگان
چکیده
منابع مشابه
Measurement of Plasma Total Homocysteine by HPLC
23 mg/L for the evaluation tube, with an average difference between tube types of 35 6 4.3 mg/L. The test results for blood lead and EP on samples collected in the evaluation tubes were clearly equivalent to those collected in the independently certified, lead-free control tubes. The availability of pediatric pretested lead-free collection tubes will contribute to accurate and reliable diagnosi...
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Recent clinical research has pointed at hyperhomocysteinemia as an independent risk factor in a number of cardiovascular and neurological diseases. We have improved a chromatographic method of total plasma homocysteine measurements in order to obtain higher sensitivity, reliability and reproducibility. The method demonstrates excellent linearity (R=0.999), range (<2-100 microM), precision (inst...
متن کاملRegular paper Improved HPLC method for total plasma homocysteine detection and quantification
Recent clinical research has pointed at hyperhomocysteinemia as an independent risk factor in a number of cardiovascular and neurological diseases. We have improved a chromatographic method of total plasma homocysteine measurements in order to obtain higher sensitivity, reliability and reproducibility. The method demonstrates excellent linearity (R = 0.999), range (< 2–100 μM), precision (instr...
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known naturally occurring degradation product may be of interest with respect to the etiology of neural tube defects or the homocysteinemia that is associated with this variant. At a more practical level, the comparative evaluation of the two assays reported here indicates that folate concentrations are not being measured accurately by one of the assays in the 5% to 15% of people who are homozy...
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The distribution of total plasma homocysteine concentrations in relation to the sex and age is described, in a population of Shiraz, South West of Iran and compared to those reported in other populations. Two hundred and one healthy males and 201 healthy females aged >15 y were randomly selected. Total Plasma homocysteine concentrations were measured using high performance liquid chromatograp...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 1999
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/45.1.150